Assignment of Zfp100 to murine chromosome 4 band D3/E1 with radiation hybrid mapping.

Zinc finger genes have been shown to be involved in many different functions of the organism, such as development, differentiation (Krempler et al., 1999) and cancer (Stein et al., 1999). The human zinc finger gene ZNF151, has high homology to a murine POZ/zinc finger transcription factor gene, Zfp100, which is expressed in most tissues. Peukert et al. (1997) found that ZNF151 has a potent growth reducing effect on HeLa cells. Although the function of Zfp100 remains to be elucidated, it is tempting to speculate that Zfp100 codes for a protein that may play an important role in development. Here we report the assignment of the murine Zfp100 gene to chromosome 4 by radiation hybrid mapping